Breakpoint cluster region protein-like
WebApr 5, 2024 · The unstable region includes a number of residues that, when mutated, confer imatinib resistance by an unknown mechanism. ... a fusion of the breakpoint cluster region (Bcr) protein and the kinase ... WebAug 1, 2008 · 1- in a region called M-bcr (for major breakpoint cluster region), a cluster of 5.8 kb, between exons 12 and 16, also called b1 to b5 of M-bcr; most breakpoints …
Breakpoint cluster region protein-like
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WebLOC103584084 breakpoint cluster region protein-like [ (Sunda flying lemur)] Gene ID: 103584084, updated on 8-Apr-2024. Summary Other designations. breakpoint cluster region protein-like WebIn two of them, the uncharacterized XacB and XacC, the location of the domains in the sequence DH-PH-RhoGAP is similar to mammalian Bcr (breakpoint cluster region) …
WebBreakpoint cluster region. A 5.8-kb DNA segment on chromosome 22q11.23, which, in contrast to the well-studied BCR-ABL fusion protein related to malignant transformation … WebAnti-Breakpoint Cluster Region (BCR) Host: Rabbit: Immunogen: BCR (Met1042~Thr1268) Synonyms: ALL, BCR/FGFR1, BCR1, CML, FGFR1/BCR, PHL, Renal carcinoma antigen NY-REN-26: Reactivity: Mouse: Applications: ICC, IHC, IP, WB: Storage: Store at 4C for immediate use. Aliquot and store at -20C for 12 months. Avoid repeated …
WebMay 13, 2024 · The smaller derivative chromosome resulting from this translocation is commonly known as the Philadelphia (Ph) chromosome. Different chimeric BCR-ABL transcripts have been observed as a result of recombination between these regions. The presence of the e13a2 and e14a2 transcripts has been associated with chronic … WebApr 10, 2024 · The median value of breakpoint cluster region-ABL1 transcript in IS% was 13%. Seventeen (94.44%) received ALL protocol (BFM95) along with tyrosine kinase inhibitor (imatinib). One (5.56%) patient ...
WebSequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) ARBA (System generated rules) Supporting data. Select one of the options below to target your search: Literature citations;
WebApr 8, 2015 · Introduction: The World Health Organization classification of chronic myeloproliferative disease encompasses eight entities of bone marrow neoplasms, among them Breakpoint cluster region-Abelson murine leukemia viral oncogene homolog 1-positive chronic myeloid leukemia and polycythemia vera. Polycythemia vera requires, in … swr0500-mf-c02-sWebNational Center for Biotechnology Information swr 1000 antwortenWebSep 20, 2024 · The Fragile X-related disorders (FXDs), which include the intellectual disability fragile X syndrome (FXS), are disorders caused by expansion of a CGG-repeat tract in the 5′ UTR of the X-linked FMR1 gene. These disorders are named for FRAXA, the folate-sensitive fragile site that localizes with the CGG-repeat in individuals with FXS. … swr0500-mf-c02texthelp read and write appWebPR:000004712 breakpoint cluster region protein (term hierarchy) EC. 2.7.11.1. InterPro Domains. IPR037769 Abr/Bcr. IPR015123 Bcr-Abl oncoprotein oligomerisation. ... IPR011993 PH-like domain superfamily. IPR001849 Pleckstrin homology domain. IPR000198 Rho GTPase-activating protein domain. texthelp read and write gold dsa - pc/macWebNov 1, 2004 · The breakpoint cluster region protein (Bcr) is a large soluble oligomeric multidomain protein best known because of its involvement in chronic myelogenous … texthelp read and write for workWebThe fusion protein encoded by BCR-ABL varies in size, depending on the breakpoint in the BCR gene. Three breakpoint cluster regions have been characterized to date: major … texthelp read and write features