Two znf-ubp domains in isopeptidase t usp5
WebTwo ZnF-UBP domains in isopeptidase T (USP5). Biochemistry. 2012; 51: 1188-1198Barbieri I. Tzelepis K. Pandolfini L. Shi J. Open in Who Shared Wrong byline? This byline is for a different person with the same name. This byline is mine, but I want my name ... WebFeb 3, 2012 · USP5 was thought to be composed of five individual domains, including the ubiquitin diglycine-binding ZnF-UBP domain (residues 173–283, herein referred to the …
Two znf-ubp domains in isopeptidase t usp5
Did you know?
WebUSP5 was thought to be composed of five individual domains, including the ubiquitin diglycine-binding ZnF-UBP domain (residues 173−283, herein referred to the cUBP) and … WebMar 3, 2010 · Reyes-Turcu et al. (2006) reported the crystal structures of the ZNF-UBP domain of USP5 alone and in complex with ubiquitin at 2.09-angstrom resolution. They …
WebApr 12, 2024 · Ubiquitin-specific protease 5 (USP5), also known as isopeptidase T, is a DUB in the USP family. USP5 harbors a catalytic core composed of the Cys- and His-boxes, as … WebOct 24, 2024 · This result is consistent with previous reports which suggest binding of ubiquitin to the ZnF-UBD allosterically activates USP5 catalytic activity 2,3. USP5 is a …
WebMay 13, 2015 · The highest affinity site for mono-Ub binding to USP5 is believed to be at the ZnF-UBP domain, which—as an isolated domain—has been found to possess K d values … WebFeb 21, 2006 · Ubiquitin binding proteins regulate the stability, function, and/or localization of ubiquitinated proteins. Here we report the crystal structures of the zinc-finger ubiquitin …
WebHere, we determined crystal structures of the USP15 catalytic core domain, revealing a canonical USP fold, including a finger, palm, ... Two ZnF-UBP domains in isopeptidase T …
WebUbiquitin specific peptidase 5 is an enzyme that in humans is encoded by the USP5 gene. Interactions. USP5 has been shown to interact with TADA3L. References Further reading. … homes for sale near winter wisconsinWebJan 31, 2024 · Usp5 belongs to the USP family of deubiquitinating enzymes (DUBs), which comprises the largest class of DUBs. We previously reported that loss of Usp5 impairs … homes for sale near woodbury mnWebNov 1, 2024 · Through a genome-wide CRISPR screen, we identify the ERK pathway and USP5 as positive regulators of the m 6 A deposition. We find that ERK phosphorylates METTL3 at S43/S50/S525 and WTAP at S306/S341, ... Two ZnF-UBP domains in isopeptidase T (USP5). Avvakumov GV, Walker JR ... hire help to move furnitureWebTwo ZnF-UBP domains in isopeptidase T (USP5) Article. Feb 2012; George V Avvakumov; ... Sirano Dhe-Paganon; Human ubiquitin-specific cysteine protease 5 (USP5, also known as … hire help to clean out houseWebHuman Gene USP5 (uc001qri.4) Description: Homo sapiens ubiquitin specific peptidase 5 (isopeptidase T) (USP5), transcript variant 1, mRNA. RefSeq Summary (NM_001098536): Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin … homes for sale near wood river ilWebJul 1, 2008 · Isopeptidase T (IsoT/USP5) is a deubiquitinating enzyme that is largely responsible for the disassembly of unanchored polyubiquitin in the cell. IsoT has four … hirehelpzWebTwo ZnF-UBP Domains in Isopeptidase T (USP5) Author: Fang Xianyang, et al. ; Avvakumov George V.; Walker John R.; Xue Sheng; Allali-Hassani Abdellah; Asinas Abdalin; Nair Usha … hire henry